Fibrin Glue. Kshar Sutra, Phenol, RFA, and Seton Treatment of Pilonidal Disease
In a previous post I discussed several “minimally invasive” pilonidal treatments, and you can read about them here. However, there are a few other kinds of minimally invasive therapies that are worth discussion. They are:
- Fibrin Glue
- Kshar Sutra
- Phenol Injection
- RFA (Radio Frequency Ablation)
- Seton treatment
These are all addressing the pilonidal sinus tract, which is one of the more common presentations of pilonidal disease. These treatments would have no place in the treatment of a large, non-healing wound. I’ll describe each of these separately:
Fibrin Glue Treatment of Pilonidal Sinus
The sinus tract is cleaned out of hair and debris. Fibrin glue is then injected into the sinus tract to obliterate any space in the sinus tract. (Fibrin glue is a biological adhesive which consists of concentrated human fibrinogen which is activated by the addition of bovine thrombin and calcium chloride.)
Kshar Sutra Treatment of Pilonidal Sinus
The sinus tract is cleaned out, the midline pits are removed, and a medicated thread is put in the sinus tract origin, and out the sinus tract exit, and tied in a circle. It is left in place until it causes the tract to scar down and heal.
Phenol Injection for Pilonidal Sinus
This is a technique that is more popular in Europe than the United States. The sinus tract is cleaned out and some form of phenol is instilled into the tract. There are several forms of phenol such as cream-gel, liquid and crystals. Phenol is a caustic, antiseptic, germicide, and has a local anesthetic effect. (It has been used as an embalming fluid!)
RFA (Radio Frequency Ablation) of Pilonidal Sinus
In this technique the sinus is surgically removed, and an electrocautery unit is used to destroy the residual sinus tissue. As surgeons, we use electrocautery in almost every operation. It is a machine that turns electrical energy into heat energy. (often termed a “Bovie” after the inventor). In this instance, certain kinds of tips are used on the machine to facilitate the procedure.
Seton Treatment of Pilonidal Sinus
This is similar to kshar sutra, in that a thread is placed through the two ends of the sinus and tied. Patients come in weekly for the thread to be tightened, until it cuts through the tissues. The inflammation from the thread obliterates the sinus.
Cryosurgery for Pilonidal Sinus
This is very similar to using RFA or Laser – where energy is used to destroy the sinus, but in this case liquid nitrogen is used to destroy the tissues by freezing.
You may be noticing a theme here:
- They all of these put something in the sinus tract to obliterate it (chemicals, heat energy, freezing, foreign body, glue).
- They are not very different than EPSiT, SiLaC (laser surgery), pit picking, or Gips Procedure.
- They may or may not be able to be done in an office setting.
- They all require multiple post op visits.
- They do not re-shape the gluteal crease.
The literature regarding the success rates of these procedures is not the most robust. However, when the literature is evaluated the recurrence rate is reported as 15% – 40%. Many studies contain small numbers of patients and short follow up times. Of course, only surgeons with good results report their outcomes, and many surgeons don’t write papers about this at all!
My take on all of these minimally invasive procedures is:
- They are are a reasonable first step in a specific group of patients with a SHALLOW CLEFT who present with ONLY a sinus or two.
- They are NOT an option when dealing with open wounds and non-healing surgery.
- The patient has to accept that there is a significant failure rate. At best one out of five patients will fail, and more likely two out of three (Update: an article from June 2022 has demonstrated a 62% failure rate of pit picking at five years. You can download and read the article by following this link).
- None of these procedures has been shown to be significantly better than the others.
- Although they may cause some minor scarring and distortion, they do maintain the original shape of the gluteal cleft, if that is of cosmetic importance to the patient.
- They are not widely accepted by surgeons, and it may be difficult to find one to perform the procedure.
- In almost all situations, if they fail, a cleft-lift is still a future option.
I do not perform any of these operations, because I do not feel that the success rate is worth the time, expense and discomfort for a procedure with a low success rate. Especially, if it requires travel across the country to see me. If you are interested in these minimally invasive procedure, I suggest you try to find someone local to evaluate and treat you. If the minimally invasive therapy fails, then come see me for a cleft-lift.